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The similarities in disease mechanisms across species are striking, and as a result, many veterinary drugs used to treat animals are either identical or closely related to those used for human treatment

4e and Supplementary Data 3), just as occurred in Gclc -sufficient MZB (Fig

In a cellular model of CF, ASOs were designed to target the inhibitory secondary mRNA structures in the uORF of the 5 UTR on the CFTR mRNA transcripteffectively increasing both the expression and function of CFTR [88]

However, ASCT2 has also anticancer properties [26], because its deletion can lead to apoptosis of leukemia cells [27]

This approach would help in a more balanced way